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Coronal brain slices (300 m) were prepared using a vibrating microtome (VT1200s, Leica) and incubated in oxygenated HEPES ACSF solution (28 C) for at least 1 hour

If metabolites were classified as rhythmic in both groups, the Circacompare mixed model was used to detect differences in mean levels and amplitude and to detect phase shifts

In either case, with this condition, the patients spinal canal narrows, leading to less open space surrounding the spinal cord and nerves

Based on huge promising data on using neutralizing antibodies against SARS-CoV and MERS-CoV, it seems that m-Abs could provide promising treatment results in COVID-19 as well [73]

7.5.5 Outcome measurement and definition heterogeneity Substantial heterogeneity exists in how primary outcomes are defined and measured across studies