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A., Saber, S., Raafat, E
VAT regulates whole body metabolism by the release of the hormone adiponectin, which redistributes fat deposited ectopically in the liver and muscle to the SAT depots, and by the hormone leptin, which reduces appetite and augments energy expenditure, controlling energy homeostasis [61,65]
In ALS, pathological intronic hexanucleotide GGGGCC expansions in the C9orf72 gene are thought to contribute to neurodegeneration by multiple mechanisms, including toxic cytoplasmic dipeptide repeat protein aggregates, toxic RNA gain-of-function, or loss of function due to haploinsufficiency [20, 21]
KDIGO 2022 Clinical Practice Guideline for diabetes management in chronic kidney disease
Redox Biol 1(4):180183 Gluchowski NL, Becuwe M, Walther TC, Farese RV (2017) Lipid droplets and liver disease: from basic biology to clinical implications
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