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Moreover, the leukemia-on chip allowed the study of the spatial heterogeneity in the leukemic niche as well as to investigate the mechanisms underlying the leukemia survival across different patient-derived samples

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We could demonstrate that mast cells from AD patients showed a significantly higher baseline mRNA expression of H2R (12,5-fold) and H4R (5,0-fold) when compared to mast cells from HVs (Fig