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Hypotension and orthostatic hypotension were more frequently seen in patients on concomitant antihypertensive therapy

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Conclusions BPC-157 was effective during phase 1 but not during phase 2, as determined by the formalin test

224 Mechanistically, mGluRs can directly regulate glutamatergic signalling by anchoring in complexes with SHANK and HOMER proteins and further control the synthesis of synaptic proteins via activation of the PI3K/AKT/mTOR pathways