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When you have an MTHFR mutation , your enzyme might be less efficient at converting folic acid into the active form your body needs: 5-methyltetrahydrofolate (5-MTHF)

Choose complex carbohydrates that are rich in fiber and nutrients, such as whole grains, fruits, vegetables, and legumes

Peptides were extracted from each sample using HyperSep C18 tips (Thermo Scientific), and 50 g and 350 g were kept for total proteomics and phosphoproteomics analysis, respectively

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Of the 48 inter-molecular NOE restraints, only 2 NOEs could be assigned unambiguously and correspond to contacts between p53-Trp53 HE# - FOXO4-Leu160 HD# and p53-Trp53 HD#FOXO4-Leu109 HD# (Supplementary Note 1)