Drucker, Senior Investigator at the Lunenfeld-Tanenbaum Research Institute, shares the prize with four colleagues from the United States and Denmark who were also involved in GLP1s journey from the lab to pharmacies
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Hypoglycemia (low plasma glucose) is dangerous because the brain needs glucose for proper functioning
Several disorders show time-dependent variations: Hypertension Early morning blood pressure surge Asthma Symptoms worsen at night Rheumatoid arthritis Morning stiffness Peptic ulcer Increased nocturnal acid secretion Administering medications in alignment with these biological rhythms can: Improve therapeutic efficacy Reduce adverse effects Lower required doses Enhance patient compliance Two important related concepts: Chronopharmacokinetics Time-dependent changes in drug absorption, distribution, metabolism, and excretion Chronopharmacodynamics Time-dependent variation in drug response Chronotherapeutics reminds us that personalized medicine is not only about selecting the right drug its also about choosing the right time
It contributes to the protection of cells from oxidative stress and plays a role in the maintenance of normal hair and nails.* *Authorised health claims per the EU Register of Nutrition and Health Claims
