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Keeping the barrier healthy while introducing new actives is always smart strategy

Several mechanisms have been proposed to explain the association between diabetes and cancer, such as hyperglycemia, hyperinsulinemia, increased bioactivity of insulin-like growth factor 1, oxidative stress, sex hormone dysregulation, and chronic inflammation [37]

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In this group of patients, an increase of N/OFQ in the sputum, sub-epithelium, and extracellular matrix have been observed compared to the control group or patients with mild asthma (Singh et al., 2016)

The tangle of nuclear receptors that controls xenobiotic metabolism and transport: crosstalk and consequences