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The second case highlights a patient on a stable dose of potassium replacement and chlorthalidone who required additional potassium supplementation once initiated on semaglutide

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Alternatively, cytoplasmic CE is packaged into autophagosomes, which are trafficked to lysosomes, where the CE is hydrolyzed by acid lipase(73,74), generating free cholesterol that is made available for efflux mainly via ABCA1(Figure 2) (73,74)