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They indicate that although cannabis effect on driver impairment is moderate in comparison to alcohol effects, using cannabis and alcohol together may have an enhanced effect on driver impairment

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Inhalation Toxicology 22 , 199209, (2010)

The disruption of hormonal balance can also cause other menstrual disorders, such as amenorrhea (absence of menstruation) and oligomenorrhea (infrequent menstruation), which can complicate the journey to conception