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Severe or worsening symptoms: Extensive redness, swelling, fissures, or ulcerations may indicate complicated infection requiring prescription antifungal therapy rather than over-the-counter treatments

Adjunctive atypical antipsychotic treatment for major depressive disorder: a meta-analysis of depression, quality of life, and safety outcomes

Weight effects: Meta-analyses show average weight loss of 1-3 pounds over 12 weeksstatistically significant but clinically modest 12 Ye, Y

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doi: 10.1007/s12011-015-0304-9 99 WangKWeiHZhangWLiZDingLYuTet al