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The data mentioned above indicate that the pathogenic potential of specific microorganisms in IBD is subject to multifactorial regulation, encompassing genetic background, environmental factors, and the composition of the gut microbiota

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PMID: 16928994 Loeys BL, Chen J, Neptune ER, Judge DP, Podowski M, Holm T, Meyers J, Leitch CC, Katsanis N, Sharifi N, Xu FL, Myers LA, Spevak PJ, Cameron DE, De Backer J, Hellemans J, Chen Y, Davis EC, Webb CL, Kress W, Coucke P, Rifkin DB, De Paepe AM, Dietz HC