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Nutrients like glucose, amino acids, and nucleotides can be transported via this mechanism[34]

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In addition, the availability of folates and B12 in their activated forms, i.e., methylfolate and methylcobalamin, may increase their actual metabolic suitability by escaping the common genetic variants of the respective activating enzymes Methylene TetraHydroFolate Reductase (MTHFR) and Methionine Synthase Reductase (MTRR) [15, 16]