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We observed that the dramatic increase in mitochondrial lipid peroxidation induced by LDHB silencing is not only associated with shrunken mitochondria featuring decreased crista and condensed/ruptured membranes, a phenotype associated with the induction of ferroptosis 28,29 but also with the accumulation of autophagosomes (Fig

One intriguing interpretation is that this allows FBFs to simultaneously control the rate of both SPC proliferation and differentiation, thus maintaining the balance between these two cell fates

It means less variability between subjects and more reliable, reproducible data

34 WangW.WangQ.QiX.GurneyM.PerryG.VolkowN