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In studies examining exercise performance, combined supplementation of vitamin C and glutathione demonstrated: [10] Decreased heart rate during exercise Reduced carbon dioxide output Improved skeletal muscle oxygenation Attenuation of exercise-induced oxidative stress markers These benefits weren't observed to the same degree when either antioxidant was supplemented alone, underscoring the synergistic relationship

FEMS Microbiol Rev 14:303308 Dellarco V (1988) A mutagenicity assessment of acetaldehyde

However, experts also show caution in the use of glutathione for cosmetic purposes

Semaglutide, type 2 diabetes, and the risk of nonarteritic anterior ischemic optic neuropathy

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