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6-AH family members were found to act as mimics of the dimerization domain of FIGF (hinge region), and inhibited the interaction of an HGF molecule with a 3 H-hinge region peptide resulting in an attenuated capacity of HGF to activate its receptor Met

In rabbits and cynomolgus monkeys administered semaglutide during organogenesis, early pregnancy losses and structural abnormalities were observed at below the MRHD (rabbit) and 5-fold or greater the MRHD (monkey)

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Prophylactic creatine administration mediates neuroprotection in cerebral ischemia in mice