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10.1007/s11427-023-2532-5 27 LiL.ZhaoY.DingY.GuoL.DaiR.ChenA.et al (2025)

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Completed research The clinical development program has generated substantial human data: Phase 1 safety studies in healthy volunteers Phase 2 trials in sarcoidosis with small fiber neuropathy Phase 2b trials evaluating corneal nerve regeneration Phase 2 trials in type 2 diabetes with neuropathy Multiple ophthalmic studies This represents significantly more human research than most peptides available to researchers

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Histopathological alterations, such as glycoprotein secretion, goblet-cell hyperplasia, eosinophil infiltration, and airway remodeling, were inhibited