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18 Prevention Because of potential interactions from prolonged medication use, physicians should consider screening patients for vitamin B 12 deficiency if they have been taking proton pump inhibitors or H 2 blockers for more than 12 months, or metformin for more than four months

healthcare professionals do not prescribe it, and its use falls outside established medical practice

That said, some clients may experience mild, temporary side effects particularly if NAD+ is infused too quickly

At age 20, plasma concentrations average around 200 ng/mL