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Kim, Jae Kwang, and Sang Un Park

Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment.

Developed by researchers in Australia, AOD-9604 was initially investigated as a potential anti-obesity drug due to its ability to stimulate lipolysis (fat breakdown) and inhibit lipogenesis (fat accumulation)

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In high L-arginine-dependent tumors, such as breast cancer (Abdelmagid et al., 2013), and HCC (Kishikawa et al., 2015), increased expression of the transporter CAT-1 ( SLC7A1 ) has been observed, and CAT-1 ( SLC7A1 ) knockdown decreases the viability of cancer cells and induces apoptosis