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PT-141 binds primarily to MC4R receptors in hypothalamic brain regions particularly the medial preoptic area and paraventricular nucleus associated with sexual arousal and motivation

Both PLT ( Supplementary Table 1 ) and PCT ( Supplementary Table 1 ) decreased after LPS administration, reaching their nadir at 6 h and 12 h, respectively and returned thereafter to pre-challenge levels

In our research, the effectiveness of PDA@Pt as an anti-inflammatory agent was confirmed through comprehensive real-time fluorescence quantitative analysis (qRT-PCR) and immunofluorescence experiments

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Generally, it can be stated that follicular targeting of actives is becoming a promising tool in dermatotherapy [35]