Although current evidence supports broad applicability across BMI, diabetes status, and fibrosis stages F2-F3, subgroup analyses suggest attenuated responses in non-obese patients and in certain ethnic groups (Hispanic patients in ESSENCE), emphasizing the need for precision medicine approaches incorporating anthropometric, genetic (e.g., PNPLA3, HSD17B13), and metabolic profiling
doi: 10.1046/j.1365-2230.2003.01207.x
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5e compared to sham-operated WD mice in Supplementary Fig
Ozempic in clinical trials The SUSTAIN clinical trial program tested Ozempic across more than 8,000 patients in over a dozen studies