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As a member of the GPX family, it catalyzes the reduction of glutathione (GSH), detoxifies water-soluble lipid hydroperoxide and protects cells

FDA labeling for EGRIFTA WR states that tesamorelin is indicated for reducing excess abdominal fat in HIV-infected adults with lipodystrophy, while also noting that it is not indicated for weight-loss management and that long-term cardiovascular safety has not been established. For a research comparison article, Tesamorelin gives useful context: it shows that the GHRH analog category is not limited to CJC-1295 and Sermorelin

The company already has experience making generic versions of liraglutide, and its formulation of that peptide was approved for sale in the US this year

Annie Moore, an internal medicine physician at the CU Anschutz School of Medicine

Minireview: update on incretin biology: focus on glucagon-like peptide-1