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The FDA has documented cases where patients administered 5 to 20 times their prescribed dose from compounded multi-dose vials
Note bowel movements (frequency/consistency), pain episodes, nausea severity, etc
The isoelectric point of semaglutide sits around pH 5.4, and degradation accelerates significantly between pH 4.5 and 5.5, which means that any formulation changes caused by temperature exposure can compound the problem by shifting the solution toward less stable conditions
They're known as GLP-1 agonists
Injection site reactions are not applicable to this orally disintegrating tablet formulation, representing an advantage over injectable GLP-1 receptor agonists
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