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Coordinated pathological changes include fibrosis, stromal stiffening, and myofibroblast expansion in both compartments, which compromise joint biomechanics and serve as sources of persistent nociceptive signaling (Tang et al., 2024
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Thats why were using these two agents, one of which targets bone and the other cancer, and both of which prolong survival independently, to see if those effects can be amplified by giving them together
Despite media narratives that often frame GLP-1 drugs as empowering, over half of women (52%) and more than a third of men (37%) believe users are judged negatively, seen as taking the easy way out