I want to spend a little bit of more time on some of the potential side effects because we went over them a little bit
Both trigger systemic inflammation and immune dysregulation, leading to symptoms such as fatigue, brain fog, headaches, joint pain, and anxiety
Whiskers defines as minima Q1 1.5* interquartile range and maxima Q3 + 1.5* interquartile range
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HRT and GLP-1: What Women Need to Know About Combining These Therapies At a glance Primary GLP-1 agents used with HRT / semaglutide 2.4 mg (Wegovy) and tirzepatide 15 mg (Zepbound) Mean weight loss with semaglutide 2.4 mg / 14.9% at 68 weeks in STEP-1 (N=1,961) Estrogen effect on visceral fat / transdermal 17-beta-estradiol reduces visceral adiposity by ~6-7% vs placebo per RCT data Oral estrogen risk with GLP-1 / slowed gastric emptying may reduce absorption
