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When GLP-1 binds to its receptor, it activates Akt, which subsequently inhibits GSK3 and reduces the accumulation of harmful proteins, such as -synuclein

Interestingly, the effect on blood glucose during OGTT was especially pronounced in combination therapy groups, particularly after eight weeks of treatment, supporting that the peptides act though complimentary pathways, and possibly that the combination leads to increased durability of the glucoregulatory effects compared to stand-alone treatment, consistent with the study by [28]

The expression of Cx32 and Cx43 decreased during the H

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