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Those with a higher BMI at the start and more irregular menstrual cycles tend to see the most noticeable improvements with long-term Metformin use

However, no significant changes in gut microbiota composition were detected (Brenner et al., 2020)

Antioxidants: Scientific Literature Landscape Analysis

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To date, no clear clinical evidence has suggested a tumorigenic effect of GLP-1 RAs [24-26], yet the steadily increasing use of these agents worldwide emphasizes the importance of thoroughly evaluating their potential association with cancer risk