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Karlstaedt A, Khanna R, Thangam M, Taegtmeyer H (2020) Glucose 6-phosphate accumulates via phosphoglucose isomerase inhibition in heart muscle

mild: (025%), moderate: (26-50%), good: (51-75%), excellent: (76100%) Patients were followed-up for three months after the end of treatment period

What makes sense is that persistent HO-1 stimulation diminishes hyperglycemia and enhances glucose metabolism while shielding renal tissues, partially or entirely, against hyperglycemic injuries

The 90-day follow-up is unusually long for a peptide study and showed continued benefit rather than plateau

doi:10.17245/jdapm.2022.22.2.97 Sikiric P, Seiwerth S, Rucman R, et al