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NAD+ IV infusions deliver a higher dose slowly over time and are often chosen for more comprehensive cellular support

119,123 However, given the dynamic environment of the knee and the low residence time of small molecules in the synovial space, delivery and retention of molecules to positively impact cartilage regeneration before being cleared remains a challenge

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Bromelain is a powerful digestive enzyme commonly found and extracted from pineapples, fruits, leaves and stems