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Diagnosis is established through history, with ongoing efforts in translational research to establish the earlier diagnosis.Tau protein plays an important role in the stabilization of microtubules and converts 6S dimers of tubulin into the 36s rings required for microtubule polymerization, resulting in localization at axons of neurons under normal physiological conditions (Weingarten et al., 1975b)

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Drug metabolism and toxicity Glutathione plays a dual role in drug metabolism and detoxification