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A randomized crossover trial (12 healthy men) found that nicotine gum reduced hunger and increased fullness, and that caffeine appeared to amplify those appetite effects

The results showed that although most adolescents were aware of the dangers of e-cigarettes, the perceptions of e-cigarettes between adolescents who used and did not use e-cigarettes were different, and the descriptions from the control group were more specific and detailed than the case group

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He argued that the goal of the study was to look at what happened to smokers who switched, not to compare them to those who did not