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Building on this, our study presents the first data on the IQOS system and the 210 Po and 210 Pb radiotoxic components in smoke aerosol

Cigarette smoking: Natural history of a dependence disorder

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Upregulation of this pathway can lead to overactivation of mitophagy, affecting disease progress through multiple mechanisms, including disrupting energy metabolic balance, inducing programmed cell death, and exacerbating oxidative stress and inflammation through excessive mtROS production (Mizumura et al., 2014

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