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Also discussed are emissions from heated tobacco products and smokeless tobacco

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Tangs team had shown in a February 2018 PNAS article that e-cigarette smoke induces DNA damage in the mouse lung and bladder, and that nitrosation in cultured human lung and bladder cells converts nicotine into derivatives that increase DNA code changes, or mutations, with the potential to transform normal cells into cancer cells

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The push towards this major step is getting intense as people are becoming aware of its benefits regarding health