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Tumor-induced competition for glutamine exerts a formidable impact on immune cells, as cancer cells' secretion of glutamate not only disrupts T cell activation and promotes an immunosuppressive phenotype in neutrophils and MDSCs but also facilitates a shift towards an M2 macrophage phenotype

Role of OS in Neuroinflammation and Epilepsy Not only are ROS potentially damaging, but they also act as vital cell signalling molecules and signal transducers, playing a key regulatory role in neuronal development, excitability and synaptic plasticity [39]

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