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This is not only acceptable but often optimal

The enzyme TPH, which is accountable for the limiting step in the production of serotonin by vitamin D, is markedly induced by the metabolically active vitamin D metabolite 1,25(OH)2D in serotonergic neuron [10, 11]

These include amyloid-beta (A) plaques, hyperphosphorylated tau tangles and the transactive response DNA-binding protein of 43 kDa (TDP-43)

A distinct biological advantage All mammalian cells secrete IGF Binding Proteins (IGFBPs) which bind to and inhibit native IGF-I

"Paracetamol: a review with specific focus on the haemodynamic effects of intravenous administration"