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Understanding these is critical for any researcher: Type of Reconstitution Solvent: While Bacteriostatic Reconstitution Water (bac) is generally recommended due to its preservative properties (benzyl alcohol), using sterile water without a bacteriostatic agent will drastically shorten the shelf life, often to just a few days, due to the increased risk of microbial growth

11 In addition, Medina and colleagues found higher frequency and severity of immune-related adverse events associated with the combination of checkpoint inhibitors compared with single-agent checkpoint inhibitor therapy