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Except for this, combined with our findings that nicotine exposure significantly reduces the expression of transition proteins and protamines, interestingly, similar variations were detected in the bisphenol A-exposed testes, with inference of histone-to-protamine transition and DNA hypermethylation in spermatozoa 48

For example, current smoking prevalence in 2021/22 was about three times higher (prevalence ratio: 2.98, 95%CI: 1.61 to 5.51, adjusted for age, gender and ethnicity) among the most deprived quintile of the population compared to the most affluent quintile

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