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26 The weight-loss effects of GLP-1 RAs have been attributed not only to appetite-suppressing mechanisms but also to increased energy expenditure through activation of hindbrain pathways and stimulation of thermogenesis in brown adipose tissue

Fresenius Environ Bull 21(10):29532961

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CCXIV.The preparation of methylguanidine, and of -dimethylguanidine by the interaction of dicyanodiamide, and methylammonium and dimethylammonium chlorides respectively