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It is important to note that B12 levels should ideally be measured before commencing replacement therapy, as supplementation rapidly normalises biochemical markers, potentially obscuring the diagnosis

Furthermore, both ScWAT and OmWAT revealed a significant increase in the expression of inflammatory cytokine genes in B12 deficient subjects compared with subjects with adequate levels of B12 (Fig

Vitamin B12 is a water-soluble nutrient, which means it has an exceptionally high safety profile

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