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This timeline matches B12 pharmacokinetics: intramuscular methylcobalamin reaches peak serum concentration at 8-12 hours, but tissue saturation (particularly in the liver and nervous system) occurs over 48-72 hours as the vitamin is transported into cells and converted to active coenzyme forms (Andrs et al., 2018)

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Both sides must also file letters to the judge, recommending how she should handle defendants motions to exclude expert reports and which motions should be combined because of similar subject matters

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