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Funding This work was financially supported by a grant [2611 no.] from the Vice-Chancellor of Research, Shahrekord University of Medical Sciences (SKUMS)

Abstract: Evidence shows that the neurotransmitter dopamine mediates the rewarding effects of nicotine and other drugs of abuse, while nondopaminergic neural substrates mediate the negative motivational effects

Twin Peaks was no exception: He approached it with a little twinkle in his eye

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These companies have tried to divorce their products from real cigarettes, but the link between the real thin and the candy version is impossible to ignore