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In the rat model, the peptide was shown to exert bidirectional effects on NO synthases: stimulating eNOS (endothelial form, responsible for vasodilation) and inhibiting iNOS (inducible form, associated with inflammatory processes)

The change of aldosterone concentration was significantly larger after liraglutide than after placebo only in patients with eGFR 60 ml/min/1.73 m 2 , ( 7.3) [95%CI ( 11.7)( 0.2)] and ( 0.3) [95%CI ( 2.2)(3.8)] respectively, ( p = 0.007)

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L-carnitine deficiency: 990 mg, two to three times daily (tablets or oral solution)