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Seems like a colossal FDA blind leading the blind paper chase to me, but I suppose its a start

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Appl Sci 8:2699 Lerner CA et al (2015) Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in mouse lung

When you put in a ZYN, the nicotine will be steadily released into the bloodstream through the mucous membrane in your mouth