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Therefore, B12 deficiency should be excluded or treated before starting folic acid in patients with unexplained anaemia or neurological symptoms

This morphological variability likely affects mitochondrial functions, such as ATP production and Ca 2+ buffering

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To balance the redox state and intracellular iron homeostasis, excess intracellular Fe 2+ can be translocated out of the cell via the carrier SLC40A1 (73, 74)