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Survival analysis of a Cancer Genome Atlas (TCGA) lung cancer dataset demonstrated that high expression of acetylcholine receptors (AChRs) gene family such as CHRM2, CHRM3, CHRNA1, CHRNA2, CHRNA6, CHRNB3, or CHRNE is associated with favorable prognosis in NSCLC adenocarcinoma, but that of CHRNA5/5nAChR or CHRNA7/7nAChR is associated with an unfavorable prognosis [41]

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