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The Global Burden of Disease (GBD) framework informs our quantification of health loss through DALYs and Mortality identifying high-priority regions, while the Social Determinants of Health perspective elucidates observed socioeconomic gradients in disease burden

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[15] [16] Factors that predispose to pneumonia include smoking, immunodeficiency, alcoholism, chronic obstructive pulmonary disease, sickle cell disease (SCD), asthma, chronic kidney disease, liver disease, and biological aging