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The tissue-specific expression data of target genes, indicative of a potential causal effect on OP, were obtained from tissue-specific eQTL datasets via the Genotype-Tissue Expression (GTEx) portal ( 18

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Eight of those headaches include features such as: Moderate to intense head pain The pain on the side of your head (one or both) Pain that throbs or pulsates Pain that gets worse when you move Nausea or vomiting Sensitivity to light and sound About 12% of Americans have migraine, and only about a third of those have chronic migraine

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