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Smart 3.0 (Panlab, Harvard Apparatus, USA) was used for behavioral analysis of OFT and EPM experiments
doi:10.1056/NEJMoa1911614
Alterations in key PD-associated proteins, including -syn, leucine-rich repeat kinase 2 (LRRK2), PINK1, parkin, DJ-1, F-box only protein 7 (FBXO7), and ATPase Cation Transporting 13A2 (ATP13A2), can disrupt mitochondrial function, leading to increased ROS production and heightened susceptibility to oxidative stress [369, 370]
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