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Immunosuppression and susceptibility to infection

This triple-agonist mechanism is what makes it potentially more effective than single-agonist peptides like semaglutide , but it also means the gastrointestinal side effects can be more intense if you start too high

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Kabel AM, Salama SA, Alghorabi AA, Estfanous RS (2020) Amelioration of cyclosporine-induced testicular toxicity by carvedilol and/or alpha-lipoic acid: Role of TGF-1, the proinflammatory cytokines, Nrf2/HO-1 pathway and apoptosis

6 Vitamin C is also secreted in breast milk thus, a higher dietary intake is recommended for lactating women to make up for this loss