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Additionally, non-invasive imaging techniques, including echocardiography and stress testing, may be warranted in patients with higher cardiovascular risk profiles or symptoms suggesting coronary heart disease

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For immunofluorescence, the primary antibodies used were monoclonal [8G9] to GLP-1, monoclonal SST antibody (#MAB2358), and monoclonal Human/Mouse Ghrelin Antibody (R&D systems #MAB8200), and the secondary antibodies were Alexa Fluor 488 AffiniPure Donkey Anti-Rat IgG and Cyanine Cy3 AffiniPure Donkey Anti-Mouse IgG from Jackson ImmunoResearch (Europe Ltd.) and were used at a final dilution of 1/300

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Serious adverse events were reported in 7.7% to 10.5% with retatrutide, compared with 5.5% with placebo