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In clinical studies, liraglutide and semaglutide both led to an average 0.3-point drop in A1c in prediabetic participants (after 56 weeks for liraglutide 5 and 68 weeks for semaglutide 6 )a small but meaningful shift for people whose blood sugar is creeping upward toward the diabetes threshold

For many people, it improves with routine habits

However, only some people who inject semaglutide reach their goals

Semaglutide has a half-life of approximately one week, meaning steady-state concentrations are not achieved until 4-5 weeks at a consistent dose

Trial and label protocols hold the current step when nausea, vomiting, constipation, reflux, or food aversion has not settled